Search Results
Overview
| Uniprot ID | Q9NWH7 |
|---|---|
| Protein Name | Spermatogenesis-associated protein 6 |
| Gene Name | SPATA6 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 388 | DRVKNVLKSHQAHQR |
Function
Required for formation of the sperm connecting piece during spermiogenesis. Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis. May be involved in myosin-based microfilament transport through interaction with myosin subunits
Protein Sequence
10
MPKVKALQCA
20
LALEISSVTC
30
PGVVLKDKED
40
IYLSICVFGQ
50
YKKTQCVPAT
60
FPLVFNARMV
70
FEKVFPDAVD
80
PGDVVTQLEY
90
DTAVFELIQL
100
VPPVGETLST
110
YDENTRDFMF
120
PGPNQMSGHH
130
DSNRQVTMRR
140
ISGLRGNAPR
150
LEFSTTSVIT
160
ECLISSRKCH
170
TQDKFIYHLA
180
PVEKSHGRLQ
190
NRTSRSQKKK
200
SKSPERSKYC
210
INAKNYEQPT
220
ISSKSHSPSP
230
YTKRRMCELS
240
EDTRRRLAHL
250
NLGPYEFKKE
260
TDKPPFVIRH
270
VDPPSPRADT
280
LLGSSGRDCE
290
RDGWSRVHND
300
HSHLGCCRPK
310
DYKVIRTPHG
320
RDFDDSLEKC
330
EEYLSPRSCS
340
KPRHSARTLL
350
VHSAPSTMPK
360
HSPSPVLNRA
370
SLRERFHSDW
380
CSPSNCDEIH
390
DRVKNVLKSH
400
QAHQRHLYDE
410
RDLEKDDELE
420
LKRSLLCRDS
430
AYDSDPEYSS
440
CQQPRGTFHL
450
DDGEYWSNRA
460
ASYKGKSHRP
470
IFENSMDKMY
480
RNLYKKACSS
ASHTQESF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0031514 | motile cilium |
| Cellular Component | GO:0120212 | sperm head-tail coupling apparatus |
| Molecular Function | GO:0032027 | myosin light chain binding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0044458 | motile cilium assembly |
| Biological Process | GO:0007283 | spermatogenesis |
Reference
[1] Yan M, Tu H, Tang S, Gai Z, Shi Q et al.. Lactylated Proteomic Analysis Reveals Functional Implications of Lysine Lactylation In Asthenozoospermia.. Mol Cell Proteomics 24(12):101439. 2025 Dec. PMID: 41192556.