Search Results
Overview
| Uniprot ID | Q9NX01 |
|---|---|
| Protein Name | Thioredoxin-like protein 4B |
| Gene Name | TXNL4B |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 7 | *MSFLLPKLTSKKEV |
Function
Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition
Protein Sequence
10
MSFLLPKLTS
20
KKEVDQAIKS
30
TAEKVLVLRF
40
GRDEDPVCLQ
50
LDDILSKTSS
60
DLSKMAAIYL
70
VDVDQTAVYT
80
QYFDISYIPS
90
TVFFFNGQHM
100
KVDYGSPDHT
110
KFVGSFKTKQ
120
DFIDLIEVIY
130
RGAMRGKLIV
140
QSPIDPKNIP
KYDLLYQDI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Cellular Component | GO:0046540 | U4/U6 x U5 tri-snRNP complex |
| Cellular Component | GO:0005682 | U5 snRNP |
| Biological Process | GO:0000244 | spliceosomal tri-snRNP complex assembly |
| Biological Process | GO:0000388 | spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.