Search Results
Overview
| Uniprot ID | Q9NX07 |
|---|---|
| Protein Name | tRNA selenocysteine 1-associated protein 1 |
| Gene Name | TRNAU1AP |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 176 | RLSVAIPKASRVKPV |
Function
Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins (PubMed:16508009). Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex (PubMed:16508009). May be involved in the methylation of tRNA(Sec) (PubMed:16508009). Enhances efficiency of selenoproteins synthesis (PubMed:16508009)
Protein Sequence
10
MAASLWMGDL
20
EPYMDENFIS
30
RAFATMGETV
40
MSVKIIRNRL
50
TGIPAGYCFV
60
EFADLATAEK
70
CLHKINGKPL
80
PGATPAKRFK
90
LNYATYGKQP
100
DNSPEYSLFV
110
GDLTPDVDDG
120
MLYEFFVKVY
130
PSCRGGKVVL
140
DQTGVSKGYG
150
FVKFTDELEQ
160
KRALTECQGA
170
VGLGSKPVRL
180
SVAIPKASRV
190
KPVEYSQMYS
200
YSYNQYYQQY
210
QNYYAQWGYD
220
QNTGSYSYSY
230
PQYGYTQSTM
240
QTYEEVGDDA
250
LEDPMPQLDV
260
TEANKEFMEQ
270
SEELYDALMD
280
CHWQPLDTVS
SEIPAMM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0000049 | tRNA binding |
| Biological Process | GO:0001514 | selenocysteine incorporation |
Reference
PMID: N/A