Search Results
Overview
| Uniprot ID | Q9NXV2 |
|---|---|
| Protein Name | BTB/POZ domain-containing protein KCTD5 |
| Gene Name | KCTD5 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 225 | SEPSEKAKILQERGS |
Function
Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex (PubMed:18573101). Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (PubMed:19361449)
Protein Sequence
10
MAENHCELLS
20
PARGGIGAGL
30
GGGLCRRCSA
40
GLGALAQRPG
50
SVSKWVRLNV
60
GGTYFLTTRQ
70
TLCRDPKSFL
80
YRLCQADPDL
90
DSDKDETGAY
100
LIDRDPTYFG
110
PVLNYLRHGK
120
LVINKDLAEE
130
GVLEEAEFYN
140
ITSLIKLVKD
150
KIRERDSKTS
160
QVPVKHVYRV
170
LQCQEEELTQ
180
MVSTMSDGWK
190
FEQLVSIGSS
200
YNYGNEDQAE
210
FLCVVSKELH
220
NTPYGTASEP
230
SEKAKILQER
GSRM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0097602 | cullin family protein binding |
| Cellular Component | GO:0031463 | Cul3-RING ubiquitin ligase complex |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Biological Process | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| Biological Process | GO:0051260 | protein homooligomerization |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.