Search Results
Overview
| Uniprot ID | Q9NYH9 |
|---|---|
| Protein Name | U3 small nucleolar RNA-associated protein 6 homolog |
| Gene Name | UTP6 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 298 | QPTTKQAKAVEVGRK |
Function
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA
Protein Sequence
10
MAEIIQERIE
20
DRLPELEQLE
30
RIGLFSHAEI
40
KAIIKKASDL
50
EYKIQRRTLF
60
KEDFINYVQY
70
EINLLELIQR
80
RRTRIGYSFK
90
KDEIENSIVH
100
RVQGVFQRAS
110
AKWKDDVQLW
120
LSYVAFCKKW
130
ATKTRLSKVF
140
SAMLAIHSNK
150
PALWIMAAKW
160
EMEDRLSSES
170
ARQLFLRALR
180
FHPECPKLYK
190
EYFRMELMHA
200
EKLRKEKEEF
210
EKASMDVENP
220
DYSEEILKGE
230
LAWIIYKNSV
240
SIIKGAEFHV
250
SLLSIAQLFD
260
FAKDLQKEIY
270
DDLQALHTDD
280
PLTWDYVARR
290
ELEIESQTEE
300
QPTTKQAKAV
310
EVGRKEERCC
320
AVYEEAVKTL
330
PTEAMWKCYI
340
TFCLERFTKK
350
SNSGFLRGKR
360
LERTMTVFRK
370
AHELKLLSEC
380
QYKQLSVSLL
390
CYNFLREALE
400
VAVAGTELFR
410
DSGTMWQLKL
420
QVLIESKSPD
430
IAMLFEEAFV
440
HLKPQVCLPL
450
WISWAEWSEG
460
AKSQEDTEAV
470
FKKALLAVIG
480
ADSVTLKNKY
490
LDWAYRSGGY
500
KKARAVFKSL
510
QESRPFSVDF
520
FRKMIQFEKE
530
QESCNMANIR
540
EYYERALREF
550
GSADSDLWMD
560
YMKEELNHPL
570
GRPENCGQIY
580
WRAMKMLQGE
590
SAEAFVAKHA
MHQTGHL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005694 | chromosome |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome |
| Cellular Component | GO:0032040 | small-subunit processome |
| Molecular Function | GO:0030515 | snoRNA binding |
| Biological Process | GO:0030490 | maturation of SSU-rRNA |
| Biological Process | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0042274 | ribosomal small subunit biogenesis |
Reference
PMID: N/A