Search Results
Overview
| Uniprot ID | Q9NYP3 |
|---|---|
| Protein Name | Protein downstream neighbor of Son |
| Gene Name | DONSON |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 457 | KARSVNVKTQALSGY |
Function
Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra-S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability
Protein Sequence
10
MALSVPGYSP
20
GFRKPPEVVR
30
LRRKRARSRG
40
AAASPPRELT
50
EPAARRAALV
60
AGLPLRPFPA
70
AGGRGGGSGG
80
GPAAARRNPF
90
ARLDNRPRVA
100
AEPPDGPARE
110
QPEAPVPFLD
120
SNQENDLLWE
130
EKFPERTTVT
140
ELPQTSHVSF
150
SEPDIPSSKS
160
TELPVDWSIK
170
TRLLFTSSQP
180
FTWADHLKAQ
190
EEAQGLVQHC
200
RATEVTLPKS
210
IQDPKLSSEL
220
RCTFQQSLIY
230
WLHPALSWLP
240
LFPRIGADRK
250
MAGKTSPWSN
260
DATLQHVLMS
270
DWSVSFTSLY
280
NLLKTKLCPY
290
FYVCTYQFTV
300
LFRAAGLAGS
310
DLITALISPT
320
TRGLREAMRN
330
EGIEFSLPLI
340
KESGHKKETA
350
SGTSLGYGEE
360
QAISDEDEEE
370
SFSWLEEMGV
380
QDKIKKPDIL
390
SIKLRKEKHE
400
VQMDHRPESV
410
VLVKGINTFT
420
LLNFLINSKS
430
LVATSGPQAG
440
LPPTLLSPVA
450
FRGATMQMLK
460
ARSVNVKTQA
470
LSGYRDQFSL
480
EITGPIMPHS
490
LHSLTMLLKS
500
SQSGSFSAVL
510
YPHEPTAVFN
520
ICLQMDKVLD
530
MEVVHKELTN
540
CGLHPNTLEQ
550
LSQIPLLGKS
560
SLRNVVLRDY
IYNWRS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005657 | replication fork |
| Cellular Component | GO:0030894 | replisome |
| Biological Process | GO:0000077 | DNA damage checkpoint signaling |
| Biological Process | GO:0006260 | DNA replication |
| Biological Process | GO:0033314 | mitotic DNA replication checkpoint signaling |
| Biological Process | GO:0007095 | mitotic G2 DNA damage checkpoint signaling |
| Biological Process | GO:0033260 | nuclear DNA replication |
| Biological Process | GO:0031297 | replication fork processing |
Reference
PMID: N/A