Search Results
Overview
| Uniprot ID | Q9NYZ3 |
|---|---|
| Protein Name | G2 and S phase-expressed protein 1 |
| Gene Name | GTSE1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 471 | PTPTNQFKIPKFSIG |
Function
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression
Protein Sequence
10
MEGGGGRDEP
20
SACRAGDVNM
30
DDPKKEDILL
40
LADEKFDFDL
50
SLSSSSANED
60
DEVFFGPFGH
70
KERCIAASLE
80
LNNPVPEQPP
90
LPTSESPFAW
100
SPLAGEKFVE
110
VYKEAHLLAL
120
HIESSSRNQA
130
AQAAKPEDPR
140
SQGVERFIQE
150
SKLKINLFEK
160
EKEMKKSPTS
170
LKRETYYLSD
180
SPLLGPPVGE
190
PRLLASSPAL
200
PSSGAQARLT
210
RAPGPPHSAH
220
ALPRESCTAH
230
AASQAATQRK
240
PGTKLLLPRA
250
ASVRGRSIPG
260
AAEKPKKEIP
270
ASPSRTKIPA
280
EKESHRDVLP
290
DKPAPGAVNV
300
PAAGSHLGQG
310
KRAIPVPNKL
320
GLKKTLLKAP
330
GSTSNLARKS
340
SSGPVWSGAS
350
SACTSPAVGK
360
AKSSEFASIP
370
ANSSRPLSNI
380
SKSGRMGPAM
390
LRPALPAGPV
400
GASSWQAKRV
410
DVSELAAEQL
420
TAPPSASPTQ
430
PQTPEGGGQW
440
LNSSCAWSES
450
SQLNKTRSIR
460
RRDSCLNSKT
470
KVMPTPTNQF
480
KIPKFSIGDS
490
PDSSTPKLSR
500
AQRPQSCTSV
510
GRVTVHSTPV
520
RRSSGPAPQS
530
LLSAWRVSAL
540
PTPASRRCSG
550
LPPMTPKTMP
560
RAVGSPLCVP
570
ARRRSSEPRK
580
NSAMRTEPTR
590
ESNRKTDSRL
600
VDVSPDRGSP
610
PSRVPQALNF
620
SPEESDSTFS
630
KSTATEVARE
640
EAKPGGDAAP
650
SEALLVDIKL
660
EPLAVTPDAA
670
SQPLIDLPLI
680
DFCDTPEAHV
690
AVGSESRPLI
700
DLMTNTPDMN
710
KNVAKPSPVV
720
GQLIDLSSPL
730
IQLSPEADKE
NVDSPLLKF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005881 | cytoplasmic microtubule |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0015630 | microtubule cytoskeleton |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0008017 | microtubule binding |
| Biological Process | GO:0030330 | DNA damage response, signal transduction by p53 class mediator |
| Biological Process | GO:0007017 | microtubule-based process |
Reference
[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.