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Overview

Uniprot IDQ9NZ43
Protein NameVesicle transport protein USE1
Gene NameUSE1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
107 RERVPATKTVHLQSR

Function

SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER

Protein Sequence

10 MAASRLELNL 20 VRLLSRCEAM 30 AAEKRDPDEW 40 RLEKYVGALE 50 DMLQALKVHA 60 SKPASEVINE 70 YSWKVDFLKG 80 MLQAEKLTSS 90 SEKALANQFL 100 APGRVPTTAR 110 ERVPATKTVH 120 LQSRARYTSE 130 MRSELLGTDS 140 AEPEMDVRKR 150 TGVAGSQPVS 160 EKQLAAELDL 170 VLQRHQNLQE 180 KLAEEMLGLA 190 RSLKTNTLAA 200 QSVIKKDNQT 210 LSHSLKMADQ 220 NLEKLKTESE 230 RLEQHTQKSV 240 NWLLWAMLII 250 VCFIFISMIL FIRIMPKLK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030137 COPI-coated vesicle
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0031201 SNARE complex
Molecular Function GO:0005484 SNAP receptor activity
Biological Process GO:0007041 lysosomal transport
Biological Process GO:0030163 protein catabolic process
Biological Process GO:0015031 protein transport
Biological Process GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
Biological Process GO:0032940 secretion by cell

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.