Search Results
Overview
| Uniprot ID | Q9P032 |
|---|---|
| Protein Name | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 |
| Gene Name | NDUFAF4 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 91 | AETCQEPKEFRLPKD |
Function
Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (PubMed:18179882, PubMed:28853723). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion
Protein Sequence
10
MGALVIRGIR
20
NFNLENRAER
30
EISKMKPSVA
40
PRHPSTNSLL
50
REQISLYPEV
60
KGEIARKDEK
70
LLSFLKDVYV
80
DSKDPVSSLQ
90
VKAAETCQEP
100
KEFRLPKDHH
110
FDMINIKSIP
120
KGKISIVEAL
130
TLLNNHKLFP
140
ETWTAEKIMQ
150
EYQLEQKDVN
160
SLLKYFVTFE
170
VEIFPPEDKK
AIRSK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0031966 | mitochondrial membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0005516 | calmodulin binding |
| Biological Process | GO:0051607 | defense response to virus |
| Biological Process | GO:0032981 | mitochondrial respiratory chain complex I assembly |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.