Search Results
Overview
| Uniprot ID | Q9P270 |
|---|---|
| Protein Name | SLAIN motif-containing protein 2 |
| Gene Name | SLAIN2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 553 | GIPVPRSKLAQPVRR |
Function
Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase
Protein Sequence
10
MEDVNSNVNA
20
DQEVRKLQEL
30
VKKLEKQNEQ
40
LRSRSGAVQG
50
AGSLGPGSPV
60
RAGASIPSSG
70
AASPRGFPLG
80
LSAKSGGGPG
90
SGPRRTSSEE
100
LRDATSLLAA
110
GEGGLLDEVE
120
PLRPDELERL
130
SGWEEEEESW
140
LYSSPKKKLT
150
PMQKSVSPLV
160
WCRQVLDYPS
170
PDVECAKKSL
180
IHKLDQTMSA
190
LKRQNLYNNP
200
FNSMSYTSPY
210
SPNASSPYSS
220
GFNSPSSTPV
230
RPPIVKQLIL
240
PGNSGNLKSS
250
DRNPPLSPQS
260
SIDSELSASE
270
LDEDSIGSNY
280
KLNDVTDVQI
290
LARMQEESLR
300
QEYAATTSRR
310
SSGSSCNSTR
320
RGTFSDQELD
330
AQSLDDEDDN
340
MHHAVYPAVN
350
RFSPSPRNSP
360
RPSPKQSPRN
370
SPRSRSPARG
380
IEYSRVSPQP
390
MISRLQQPRL
400
SLQGHPTDLQ
410
TSNVKNEEKL
420
RRSLPNLSRT
430
SNTQVDSVKS
440
SRSDSNFQVP
450
NGGIPRMQPQ
460
ASAIPSPGKF
470
RSPAAPSPLA
480
LRQPVKAFSN
490
HGSGSPGSQE
500
ITQLTQTTSS
510
PGPPMVQSTV
520
SANPPSNINS
530
ATLTRPAGTT
540
AMRSGLPRPS
550
APSAGGIPVP
560
RSKLAQPVRR
570
SLPAPKTYGS
580
MKDDSWKDGC
Y
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0036064 | ciliary basal body |
| Cellular Component | GO:0097542 | ciliary tip |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0015630 | microtubule cytoskeleton |
| Biological Process | GO:0031122 | cytoplasmic microtubule organization |
| Biological Process | GO:0007020 | microtubule nucleation |
| Biological Process | GO:0031116 | positive regulation of microtubule polymerization |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.