Search Results
Overview
| Uniprot ID | Q9R0P3 |
|---|---|
| Protein Name | S-formylglutathione hydrolase |
| Gene Name | Esd |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 200 | GPDESKWKAYDATCL |
Function
Serine hydrolase involved in the detoxification of formaldehyde
Protein Sequence
10
MALKQISSNR
20
CFGGLQKVFE
30
HSSVELKCKM
40
RFAVYLPPQA
50
ESGKCPALYW
60
LSGLTCTEQN
70
FISKSGYQQA
80
ASEHGLVVIA
90
PDTSPRGCNI
100
KGEDDSWDFG
110
TGAGFYVNAT
120
EDPWKANYRM
130
YSYVTEELPQ
140
LINANFPVDP
150
QRMSIFGHSM
160
GGHGALICAL
170
KNPGKYRSVS
180
AFAPICNPVL
190
CSWGKKAFSG
200
YLGPDESKWK
210
AYDATCLVKA
220
YSGSQIDILI
230
DQGKDDEFLS
240
NGQLLPDNFI
250
AACTEKKIPV
260
VFRLQEGYDH
270
SYYFIATFIA
280
DHIRHHAKYL
NA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0031410 | cytoplasmic vesicle |
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0052689 | carboxylic ester hydrolase activity |
| Molecular Function | GO:0016788 | hydrolase activity, acting on ester bonds |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0018738 | S-formylglutathione hydrolase activity |
| Biological Process | GO:0046294 | formaldehyde catabolic process |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.
[2] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[3] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.