Search Results
Overview
| Uniprot ID | Q9R190 |
|---|---|
| Protein Name | Metastasis-associated protein MTA2 |
| Gene Name | Mta2 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 533 | AQAPLKPKTPRGTKT |
Function
May function as a transcriptional coregulator (By similarity). Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (By similarity)
Protein Sequence
10
MAANMYRVGD
20
YVYFENSSSN
30
PYLVRRIEEL
40
NKTANGNVEA
50
KVVCLFRRRD
60
ISSSLNSLAD
70
SNAREFEEES
80
KQPGVSEQQR
90
HQLKHRELFL
100
SRQFESLPAT
110
HIRGKCSVTL
120
LNETDILNQY
130
LDKEDCFFYS
140
LVFDPVQKTL
150
LADQGEIRVG
160
CKFQAEIPDR
170
LAEGESDNRN
180
QQKMEMKVWD
190
PDNPLTDRQI
200
DQFLVVARAV
210
GTFARALDCS
220
SSIRQPSLHM
230
SAAAASRDIT
240
LFHAMDTLQR
250
NGYDLAKAMS
260
TLVPQGGPVL
270
CRDEMEEWSA
280
SEAMLFEEAL
290
EKYGKDFNDI
300
RQDFLPWKSL
310
ASIVQFYYMW
320
KTTDRYIQQK
330
RLKAAEADSK
340
LKQVYIPTYT
350
KPNPNQIISV
360
GSKPGMNGAG
370
FQKGLTCESC
380
HTTQSAQWYA
390
WGPPNMQCRL
400
CASCWIYWKK
410
YGGLKTPTQL
420
EGAARGTTEP
430
HSRGHLSRPE
440
AQSLSPYTTS
450
ANRAKLLAKN
460
RQTFLLQTTK
470
LTRLARRMCR
480
DLLQPRRAAR
490
RPYAPINANA
500
IKAECSIRLP
510
KAAKTPLKIH
520
PLVRLPLATI
530
VKDLVAQAPL
540
KPKTPRGTKT
550
PINRNQLTQN
560
RGLGGIMVKR
570
SYETMAGAGV
580
PFSANGRPLA
590
SGIRSSSQPA
600
AKRQKLNPAD
610
APNPVVFVAT
620
KDTRALRKAL
630
THLEMRRAAR
640
RPNLPLKVKP
650
TLMTVRPPVP
660
LPASSHPAST
NEPIVLED
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000781 | chromosome, telomeric region |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0042659 | regulation of cell fate specification |
| Biological Process | GO:0010762 | regulation of fibroblast migration |
| Biological Process | GO:2000736 | regulation of stem cell differentiation |
| Cellular Component | GO:0000118 | histone deacetylase complex |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0016581 | NuRD complex |
| Cellular Component | GO:0005667 | transcription regulator complex |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0004407 | histone deacetylase activity |
| Molecular Function | GO:0042826 | histone deacetylase binding |
| Molecular Function | GO:0061629 | RNA polymerase II-specific DNA-binding transcription factor binding |
| Molecular Function | GO:0043565 | sequence-specific DNA binding |
| Molecular Function | GO:0003713 | transcription coactivator activity |
| Molecular Function | GO:0003712 | transcription coregulator activity |
| Molecular Function | GO:0003714 | transcription corepressor activity |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0006338 | chromatin remodeling |
| Biological Process | GO:0051276 | chromosome organization |
| Biological Process | GO:0071514 | genomic imprinting |
| Biological Process | GO:0045892 | negative regulation of DNA-templated transcription |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
Reference
[1] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.