Search Results

Overview

Uniprot IDQ9UBT7
Protein NameAlpha-catulin
Gene NameCTNNAL1
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
84 LAVGRFVKVGEAIAN

Function

May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1)

Protein Sequence

10 MAASPGPAGV 20 GGAGAVYGSG 30 SSGFALDSGL 40 EIKTRSVEQT 50 LLPLVSQITT 60 LINHKDNTKK 70 SDKTLQAIQR 80 VGQAVNLAVG 90 RFVKVGEAIA 100 NENWDLKEEI 110 NIACIEAKQA 120 GETIAALTDI 130 TNLNHLESDG 140 QITIFTDKTG 150 VIKAARLLLS 160 SVTKVLLLAD 170 RVVIKQIITS 180 RNKVLATMER 190 LEKVNSFQEF 200 VQIFSQFGNE 210 MVEFAHLSGD 220 RQNDLKDEKK 230 KAKMAAARAV 240 LEKCTMMLLT 250 ASKTCLRHPN 260 CESAHKNKEG 270 VFDRMKVALD 280 KVIEIVTDCK 290 PNGETDISSI 300 SIFTGIKEFK 310 MNIEALRENL 320 YFQSKENLSV 330 TLEVILERME 340 DFTDSAYTSH 350 EHRERILELS 360 TQARMELQQL 370 ISVWIQAQSK 380 KTKSIAEELE 390 LSILKISHSL 400 NELKKELHST 410 ATQLAADLLK 420 YHADHVVLKA 430 LKLTGVEGNL 440 EALAEYACKL 450 SEQKEQLVET 460 CRLLRHISGT 470 EPLEITCIHA 480 EETFQVTGQQ 490 IISAAETLTL 500 HPSSKIAKEN 510 LDVFCEAWES 520 QISDMSTLLR 530 EINDVFEGRR 540 GEKYGYLSLP 550 KPMKNNANLK 560 SLKPDKPDSE 570 EQAKIAKLGL 580 KLGLLTSDAD 590 CEIEKWEDQE 600 NEIVQYGRNM 610 SSMAYSLYLF 620 TRGEGPLKTS 630 QDLIHQLEVF 640 AAEGLKLTSS 650 VQAFSKQLKD 660 DDKLMLLLEI 670 NKLIPLCHQL 680 QTVTKTSLQN 690 KVFLKVDKCI 700 TKTRSMMALL 710 VQLLSLCYKL 720 LKKLQMENNG 730 WVSVTNKDTM DSKT

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005856 cytoskeleton
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0051015 actin filament binding
Molecular Function GO:0045296 cadherin binding
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007266 Rho protein signal transduction

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.