Search Results

Overview

Uniprot IDQ9UDT6
Protein NameCAP-Gly domain-containing linker protein 2
Gene NameCLIP2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
39 AAVAASSKEGSPLHK
46 KEGSPLHKQSSGPSS
596 AQEVAGLKDKVQQAT
598 EVAGLKDKVQQATSE

Function

Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operate in the control of brain-specific organelle translocations (By similarity)

Protein Sequence

10 MQKPSGLKPP 20 GRGGKHSSPM 30 GRTSTGSASS 40 SAAVAASSKE 50 GSPLHKQSSG 60 PSSSPAAAAA 70 PEKPGPKAAE 80 VGDDFLGDFV 90 VGERVWVNGV 100 KPGVVQYLGE 110 TQFAPGQWAG 120 VVLDDPVGKN 130 DGAVGGVRYF 140 ECPALQGIFT 150 RPSKLTRQPT 160 AEGSGSDAHS 170 VESLTAQNLS 180 LHSGTATPPL 190 TSRVIPLRES 200 VLNSSVKTGN 210 ESGSNLSDSG 220 SVKRGEKDLR 230 LGDRVLVGGT 240 KTGVVRYVGE 250 TDFAKGEWCG 260 VELDEPLGKN 270 DGAVAGTRYF 280 QCPPKFGLFA 290 PIHKVIRIGF 300 PSTSPAKAKK 310 TKRMAMGVSA 320 LTHSPSSSSI 330 SSVSSVASSV 340 GGRPSRSGLL 350 TETSSRYARK 360 ISGTTALQEA 370 LKEKQQHIEQ 380 LLAERDLERA 390 EVAKATSHIC 400 EVEKEIALLK 410 AQHEQYVAEA 420 EEKLQRARLL 430 VESVRKEKVD 440 LSNQLEEERR 450 KVEDLQFRVE 460 EESITKGDLE 470 TQTQLEHARI 480 GELEQSLLLE 490 KAQAERLLRE 500 LADNRLTTVA 510 EKSRVLQLEE 520 ELTLRRGEIE 530 ELQQCLLHSG 540 PPPPDHPDAA 550 EILRLRERLL 560 SASKEHQRES 570 GVLRDKYEKA 580 LKAYQAEVDK 590 LRAANEKYAQ 600 EVAGLKDKVQ 610 QATSENMGLM 620 DNWKSKLDSL 630 ASDHQKSLED 640 LKATLNSGPG 650 AQQKEIGELK 660 AVMEGIKMEH 670 QLELGNLQAK 680 HDLETAMHVK 690 EKEALREKLQ 700 EAQEELAGLQ 710 RHWRAQLEVQ 720 ASQHRLELQE 730 AQDQRRDAEL 740 RVHELEKLDV 750 EYRGQAQAIE 760 FLKEQISLAE 770 KKMLDYERLQ 780 RAEAQGKQEV 790 ESLREKLLVA 800 ENRLQAVEAL 810 CSSQHTHMIE 820 SNDISEETIR 830 TKETVEGLQD 840 KLNKRDKEVT 850 ALTSQTEMLR 860 AQVSALESKC 870 KSGEKKVDAL 880 LKEKRRLEAE 890 LETVSRKTHD 900 ASGQLVLISQ 910 ELLRKERSLN 920 ELRVLLLEAN 930 RHSPGPERDL 940 SREVHKAEWR 950 IKEQKLKDDI 960 RGLREKLTGL 970 DKEKSLSDQR 980 RYSLIDRSSA 990 PELLRLQHQL 1000 MSTEDALRDA 1010 LDQAQQVEKL 1020 MEAMRSCPDK 1030 AQTIGNSGSA 1040 NGIHQQDKAQ KQEDKH

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005938 cell cortex
Cellular Component GO:0005875 microtubule associated complex
Cellular Component GO:0035371 microtubule plus-end
Cellular Component GO:0005634 nucleus
Molecular Function GO:0008017 microtubule binding
Molecular Function GO:0051010 microtubule plus-end binding
Biological Process GO:0031122 cytoplasmic microtubule organization

Reference

[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.