Search Results

Overview

Uniprot IDQ9UG63
Protein NameATP-binding cassette sub-family F member 2
Gene NameABCF2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
25 KARQRPRKGHEENGD
351 RFGHGSAKLARQAQS
365 SKEKTLQKMMASGLT
618 DEEPQLTKRTHNV**

Function

No function data available.

Protein Sequence

10 MPSDLAKKKA 20 AKKKEAAKAR 30 QRPRKGHEEN 40 GDVVTEPQVA 50 EKNEANGRET 60 TEVDLLTKEL 70 EDFEMKKAAA 80 RAVTGVLASH 90 PNSTDVHIIN 100 LSLTFHGQEL 110 LSDTKLELNS 120 GRRYGLIGLN 130 GIGKSMLLSA 140 IGKREVPIPE 150 HIDIYHLTRE 160 MPPSDKTPLH 170 CVMEVDTERA 180 MLEKEAERLA 190 HEDAECEKLM 200 ELYERLEELD 210 ADKAEMRASR 220 ILHGLGFTPA 230 MQRKKLKDFS 240 GGWRMRVALA 250 RALFIRPFML 260 LLDEPTNHLD 270 LDACVWLEEE 280 LKTFKRILVL 290 VSHSQDFLNG 300 VCTNIIHMHN 310 KKLKYYTGNY 320 DQYVKTRLEL 330 EENQMKRFHW 340 EQDQIAHMKN 350 YIARFGHGSA 360 KLARQAQSKE 370 KTLQKMMASG 380 LTERVVSDKT 390 LSFYFPPCGK 400 IPPPVIMVQN 410 VSFKYTKDGP 420 CIYNNLEFGI 430 DLDTRVALVG 440 PNGAGKSTLL 450 KLLTGELLPT 460 DGMIRKHSHV 470 KIGRYHQHLQ 480 EQLDLDLSPL 490 EYMMKCYPEI 500 KEKEEMRKII 510 GRYGLTGKQQ 520 VSPIRNLSDG 530 QKCRVCLAWL 540 AWQNPHMLFL 550 DEPTNHLDIE 560 TIDALADAIN 570 EFEGGMMLVS 580 HDFRLIQQVA 590 QEIWVCEKQT 600 ITKWPGDILA 610 YKEHLKSKLV 620 DEEPQLTKRT HNV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0016020 membrane
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0016887 ATP hydrolysis activity

Reference

[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[2] Guo X, Ren X, Yan C, Huang H. Quantitative Proteomics Reveals the Role of Lysine Lactylation in Lenalidomide-Resistance in Multiple Myeloma Cells.. ACS Chem Biol 20(7):1728-1738. 2025 Jul 18. PMID: 40590393.

[3] Chao L, Xu Y, Yang Y, Ao X, Liang J. Identification of lactylation-related biomarkers for diagnosis, prognosis, and treatment responsiveness in triple-negative breast cancer.. World J Surg Oncol 24(1):77. 2026 Jan 22. PMID: 41566505.

[4] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.