Search Results
Overview
| Uniprot ID | Q9UGK3 |
|---|---|
| Protein Name | Signal-transducing adaptor protein 2 |
| Gene Name | STAP2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 14 | PPRVPKPKGVLPSHY |
Function
Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity
Protein Sequence
10
MASALRPPRV
20
PKPKGVLPSH
30
YYESFLEKKG
40
PCDRDYKKFW
50
AGLQGLTIYF
60
YNSNRDFQHV
70
EKLNLGAFEK
80
LTDEIPWGSS
90
RDPGTHFSLI
100
LRDQEIKFKV
110
ETLECREMWK
120
GFILTVVELR
130
VPTDLTLLPG
140
HLYMMSEVLA
150
KEEARRALET
160
PSCFLKVSRL
170
EAQLLLERYP
180
ECGNLLLRPS
190
GDGADGVSVT
200
TRQMHNGTHV
210
VRHYKVKREG
220
PKYVIDVEQP
230
FSCTSLDAVV
240
NYFVSHTKKA
250
LVPFLLDEDY
260
EKVLGYVEAD
270
KENGENVWVA
280
PSAPGPGPAP
290
CTGGPKPLSP
300
ASSQDKLPPL
310
PPLPNQEENY
320
VTPIGDGPAV
330
DYENQDVASS
340
SWPVILKPKK
350
LPKPPAKLPK
360
PPVGPKPEPK
370
VFNGGLGRKL
380
PVSSAQPLFP
390
TAGLADMTAE
400
LQKKLEKRRA
LEH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0035591 | signaling adaptor activity |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.