Search Results
Overview
| Uniprot ID | Q9UHR4 |
|---|---|
| Protein Name | BAR/IMD domain-containing adapter protein 2-like 1 |
| Gene Name | BAIAP2L1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 272 | ERSNVVRKDYDTLSK |
| 279 | KDYDTLSKCSPKMPP |
Function
May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection
Protein Sequence
10
MSRGPEEVNR
20
LTESTYRNVM
30
EQFNPGLRNL
40
INLGKNYEKA
50
VNAMILAGKA
60
YYDGVAKIGE
70
IATGSPVSTE
80
LGHVLIEISS
90
THKKLNESLD
100
ENFKKFHKEI
110
IHELEKKIEL
120
DVKYMNATLK
130
RYQTEHKNKL
140
ESLEKSQAEL
150
KKIRRKSQGS
160
RNALKYEHKE
170
IEYVETVTSR
180
QSEIQKFIAD
190
GCKEALLEEK
200
RRFCFLVDKH
210
CGFANHIHYY
220
HLQSAELLNS
230
KLPRWQETCV
240
DAIKVPEKIM
250
NMIEEIKTPA
260
STPVSGTPQA
270
SPMIERSNVV
280
RKDYDTLSKC
290
SPKMPPAPSG
300
RAYTSPLIDM
310
FNNPATAAPN
320
SQRVNNSTGT
330
SEDPSLQRSV
340
SVATGLNMMK
350
KQKVKTIFPH
360
TAGSNKTLLS
370
FAQGDVITLL
380
IPEEKDGWLY
390
GEHDVSKARG
400
WFPSSYTKLL
410
EENETEAVTV
420
PTPSPTPVRS
430
ISTVNLSENS
440
SVVIPPPDYL
450
ECLSMGAAAD
460
RRADSARTTS
470
TFKAPASKPE
480
TAAPNDANGT
490
AKPPFLSGEN
500
PFATVKLRPT
510
VTNDRSAPII
R
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005912 | adherens junction |
| Cellular Component | GO:0005856 | cytoskeleton |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0098641 | cadherin binding involved in cell-cell adhesion |
| Molecular Function | GO:0070064 | proline-rich region binding |
| Biological Process | GO:0051764 | actin crosslink formation |
| Biological Process | GO:0051017 | actin filament bundle assembly |
| Biological Process | GO:0007009 | plasma membrane organization |
| Biological Process | GO:0030838 | positive regulation of actin filament polymerization |
| Biological Process | GO:0032956 | regulation of actin cytoskeleton organization |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.
[2] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.