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Overview

Uniprot IDQ9UID6
Protein NameZinc finger protein 639
Gene NameZNF639
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
177 EPPAKLCKILDKSQA
181 KLCKILDKSQALNVT
192 LNVTAQQKWPLLRAN

Function

Binds DNA and may function as a transcriptional repressor

Protein Sequence

10 MNEYPKKRKR 20 KTLHPSRYSD 30 SSGISRIADG 40 FNGIFSDHCY 50 SVCSMRQPDL 60 KYFDNKDDDS 70 DTETSNDLPK 80 FADGIKARNR 90 NQNYLVPSPV 100 LRILDHTAFS 110 TEKSADIVIC 120 DEECDSPESV 130 NQQTQEESPI 140 EVHTAEDVPI 150 AVEVHAISED 160 YDIETENNSS 170 ESLQDQTDEE 180 PPAKLCKILD 190 KSQALNVTAQ 200 QKWPLLRANS 210 SGLYKCELCE 220 FNSKYFSDLK 230 QHMILKHKRT 240 DSNVCRVCKE 250 SFSTNMLLIE 260 HAKLHEEDPY 270 ICKYCDYKTV 280 IFENLSQHIA 290 DTHFSDHLYW 300 CEQCDVQFSS 310 SSELYLHFQE 320 HSCDEQYLCQ 330 FCEHETNDPE 340 DLHSHVVNEH 350 ACKLIELSDK 360 YNNGEHGQYS 370 LLSKITFDKC 380 KNFFVCQVCG 390 FRSRLHTNVN 400 RHVAIEHTKI 410 FPHVCDDCGK 420 GFSSMLEYCK 430 HLNSHLSEGI 440 YLCQYCEYST 450 GQIEDLKIHL 460 DFKHSADLPH 470 KCSDCLMRFG 480 NERELISHLP VHETT

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
Molecular Function GO:0003700 DNA-binding transcription factor activity
Molecular Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular Function GO:0000976 transcription cis-regulatory region binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0043923 host-mediated activation of viral transcription
Biological Process GO:0043922 host-mediated suppression of viral transcription
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:0030307 positive regulation of cell growth
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0046718 symbiont entry into host cell

Reference

[1] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.