Search Results
Overview
| Uniprot ID | Q9UIX4 |
|---|---|
| Protein Name | Voltage-gated potassium channel regulatory subunit KCNG1 |
| Gene Name | KCNG1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 293 | RLIQAPSKFAFLRSP |
Function
Regulatory alpha-subunit of the voltage-gated potassium (Kv) channel which, when coassembled with KCNB1 or KCNB2, can modulate their expression and their gating kinetics by acting on deactivation upon repolarization and inactivation during maintained depolarization (PubMed:19074135). Potassium channel subunit that does not form functional channels by itself (PubMed:19074135)
Protein Sequence
10
MTLLPGDNSD
20
YDYSALSCTS
30
DASFHPAFLP
40
QRQAIKGAFY
50
RRAQRLRPQD
60
EPRQGCQPED
70
RRRRIIINVG
80
GIKYSLPWTT
90
LDEFPLTRLG
100
QLKACTNFDD
110
ILNVCDDYDV
120
TCNEFFFDRN
130
PGAFGTILTF
140
LRAGKLRLLR
150
EMCALSFQEE
160
LLYWGIAEDH
170
LDGCCKRRYL
180
QKIEEFAEMV
190
EREEEDDALD
200
SEGRDSEGPA
210
EGEGRLGRCM
220
RRLRDMVERP
230
HSGLPGKVFA
240
CLSVLFVTVT
250
AVNLSVSTLP
260
SLREEEEQGH
270
CSQMCHNVFI
280
VESVCVGWFS
290
LEFLLRLIQA
300
PSKFAFLRSP
310
LTLIDLVAIL
320
PYYITLLVDG
330
AAAGRRKPGA
340
GNSYLDKVGL
350
VLRVLRALRI
360
LYVMRLARHS
370
LGLQTLGLTA
380
RRCTREFGLL
390
LLFLCVAIAL
400
FAPLLYVIEN
410
EMADSPEFTS
420
IPACYWWAVI
430
TMTTVGYGDM
440
VPRSTPGQVV
450
ALSSILSGIL
460
LMAFPVTSIF
470
HTFSRSYLEL
480
KQEQERVMFR
490
RAQFLIKTKS
500
QLSVSQDSDI
510
LFGSASSDTR
DNN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0008076 | voltage-gated potassium channel complex |
| Molecular Function | GO:0015459 | potassium channel regulator activity |
| Molecular Function | GO:0005249 | voltage-gated potassium channel activity |
| Biological Process | GO:0001508 | action potential |
| Biological Process | GO:0071805 | potassium ion transmembrane transport |
| Biological Process | GO:0006813 | potassium ion transport |
| Biological Process | GO:0051260 | protein homooligomerization |
| Biological Process | GO:1901379 | regulation of potassium ion transmembrane transport |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.