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Overview

Uniprot IDQ9UK41
Protein NameVacuolar protein sorting-associated protein 28 homolog
Gene NameVPS28
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
58 ALEKAYIKDCVSPSE
98 SIDEFCRKFRLDCPL

Function

Component of the ESCRT-I complex, a regulator of vesicular trafficking process

Protein Sequence

10 MFHGIPATPG 20 IGAPGNKPEL 30 YEEVKLYKNA 40 REREKYDNMA 50 ELFAVVKTMQ 60 ALEKAYIKDC 70 VSPSEYTAAC 80 SRLLVQYKAA 90 FRQVQGSEIS 100 SIDEFCRKFR 110 LDCPLAMERI 120 KEDRPITIKD 130 DKGNLNRCIA 140 DVVSLFITVM 150 DKLRLEIRAM 160 DEIQPDLREL 170 METMHRMSHL 180 PPDFEGRQTV 190 SQWLQTLSGM 200 SASDELDDSQ 210 VRQMLFDLES 220 AYNAFNRFLH A

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005769 early endosome
Cellular Component GO:0005768 endosome
Cellular Component GO:0010008 endosome membrane
Cellular Component GO:0000813 ESCRT I complex
Cellular Component GO:0070062 extracellular exosome
Cellular Component GO:0031902 late endosome membrane
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0044877 protein-containing complex binding
Molecular Function GO:0043130 ubiquitin binding
Biological Process GO:0016236 macroautophagy
Biological Process GO:0090148 membrane fission
Biological Process GO:0036258 multivesicular body assembly
Biological Process GO:0031397 negative regulation of protein ubiquitination
Biological Process GO:0045732 positive regulation of protein catabolic process
Biological Process GO:2000397 positive regulation of ubiquitin-dependent endocytosis
Biological Process GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Biological Process GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
Biological Process GO:0039702 viral budding via host ESCRT complex

Reference

PMID: N/A