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Overview

Uniprot IDQ9UL40
Protein NameZinc finger protein 346
Gene NameZNF346
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
287 MQRQPIQKDSTTLED

Function

Binds with low affinity to dsDNA and ssRNA, and with high affinity to dsRNA, with no detectable sequence specificity (PubMed:24521053). May bind to specific miRNA hairpins (PubMed:28431233)

Protein Sequence

10 MEYPAPATVQ 20 AADGGAAGPY 30 SSSELLEGQE 40 PDGVRFDRER 50 ARRLWEAVSG 60 AQPVGREEVE 70 HMIQKNQCLF 80 TNTQCKVCCA 90 LLISESQKLA 100 HYQSKKHANK 110 VKRYLAIHGM 120 ETLKGETKKL 130 DSDQKSSRSK 140 DKNQCCPICN 150 MTFSSPVVAQ 160 SHYLGKTHAK 170 NLKLKQQSTK 180 VEALHQNREM 190 IDPDKFCSLC 200 HATFNDPVMA 210 QQHYVGKKHR 220 KQETKLKLMA 230 RYGRLADPAV 240 TDFPAGKGYP 250 CKTCKIVLNS 260 IEQYQAHVSG 270 FKHKNQSPKT 280 VASSLGQIPM 290 QRQPIQKDST TLED

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0003725 double-stranded RNA binding
Molecular Function GO:0019899 enzyme binding
Molecular Function GO:0035198 miRNA binding
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0008270 zinc ion binding

Reference

PMID: N/A