Search Results
Overview
| Uniprot ID | Q9ULW3 |
|---|---|
| Protein Name | Activator of basal transcription 1 |
| Gene Name | ABT1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 242 | RLATAQDKARSNKGL |
| 247 | QDKARSNKGLLARIF |
Function
Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity)
Protein Sequence
10
MEAEESEKAA
20
TEQEPLEGTE
30
QTLDAEEEQE
40
ESEEAACGSK
50
KRVVPGIVYL
60
GHIPPRFRPL
70
HVRNLLSAYG
80
EVGRVFFQAE
90
DRFVRRKKKA
100
AAAAGGKKRS
110
YTKDYTEGWV
120
EFRDKRIAKR
130
VAASLHNTPM
140
GARRRSPFRY
150
DLWNLKYLHR
160
FTWSHLSEHL
170
AFERQVRRQR
180
LRAEVAQAKR
190
ETDFYLQSVE
200
RGQRFLAADG
210
DPARPDGSWT
220
FAQRPTEQEL
230
RARKAARPGG
240
RERARLATAQ
250
DKARSNKGLL
260
ARIFGAPPPS
270
ESMEGPSLVR
DS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005667 | transcription regulator complex |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0003713 | transcription coactivator activity |
| Biological Process | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0000472 | endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0034462 | small-subunit processome assembly |
| Biological Process | GO:0006366 | transcription by RNA polymerase II |
Reference
[1] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.