Search Results
Overview
| Uniprot ID | Q9UM21 |
|---|---|
| Protein Name | Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A |
| Gene Name | MGAT4A |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 85 | GSKDALNKFSDNTLK |
Function
Glycosyltransferase that catalyze the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains (PubMed:17006639). Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells (By similarity)
Protein Sequence
10
MRLRNGTVAT
20
ALAFITSFLT
30
LSWYTTWQNG
40
KEKLIAYQRE
50
FLALKERLRI
60
AEHRISQRSS
70
ELNTIVQQFK
80
RVGAETNGSK
90
DALNKFSDNT
100
LKLLKELTSK
110
KSLQVPSIYY
120
HLPHLLKNEG
130
SLQPAVQIGN
140
GRTGVSIVMG
150
IPTVKREVKS
160
YLIETLHSLI
170
DNLYPEEKLD
180
CVIVVFIGET
190
DIDYVHGVVA
200
NLEKEFSKEI
210
SSGLVEVISP
220
PESYYPDLTN
230
LKETFGDSKE
240
RVRWRTKQNL
250
DYCFLMMYAQ
260
EKGIYYIQLE
270
DDIIVKQNYF
280
NTIKNFALQL
290
SSEEWMILEF
300
SQLGFIGKMF
310
QAPDLTLIVE
320
FIFMFYKEKP
330
IDWLLDHILW
340
VKVCNPEKDA
350
KHCDRQKANL
360
RIRFRPSLFQ
370
HVGLHSSLSG
380
KIQKLTDKDY
390
MKPLLLKIHV
400
NPPAEVSTSL
410
KVYQGHTLEK
420
TYMGEDFFWA
430
ITPIAGDYIL
440
FKFDKPVNVE
450
SYLFHSGNQE
460
HPGDILLNTT
470
VEVLPFKSEG
480
LEISKETKDK
490
RLEDGYFRIG
500
KFENGVAEGM
510
VDPSLNPISA
520
FRLSVIQNSA
530
VWAILNEIHI
KKATN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005788 | endoplasmic reticulum lumen |
| Cellular Component | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0000139 | Golgi membrane |
| Cellular Component | GO:0005795 | Golgi stack |
| Cellular Component | GO:0005777 | peroxisome |
| Molecular Function | GO:0008375 | acetylglucosaminyltransferase activity |
| Molecular Function | GO:0008453 | alanine-glyoxylate transaminase activity |
| Molecular Function | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Biological Process | GO:0009101 | glycoprotein biosynthetic process |
| Biological Process | GO:0046487 | glyoxylate metabolic process |
| Biological Process | GO:0006491 | N-glycan processing |
| Biological Process | GO:0006487 | protein N-linked glycosylation |
| Biological Process | GO:0019082 | viral protein processing |
Reference
PMID: N/A