Search Results
Overview
| Uniprot ID | Q9UNL2 |
|---|---|
| Protein Name | Translocon-associated protein subunit gamma |
| Gene Name | SSR3 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 103 | VSKEVTRKLSEADNR |
| 8 | MAPKGSSKQQSEEDL |
| 98 | KREDAVSKEVTRKLS |
Function
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins
Protein Sequence
10
MAPKGSSKQQ
20
SEEDLLLQDF
30
SRNLSAKSSA
40
LFFGNAFIVS
50
AIPIWLYWRI
60
WHMDLIQSAV
70
LYSVMTLVST
80
YLVAFAYKNV
90
KFVLKHKVAQ
100
KREDAVSKEV
110
TRKLSEADNR
120
KMSRKEKDER
130
ILWKKNEVAD
140
YEATTFSIFY
150
NNTLFLVVVI
160
VASFFILKNF
170
NPTVNYILSI
180
SASSGLIALL
STGSK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Biological Process | GO:0031204 | post-translational protein targeting to membrane, translocation |
| Biological Process | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.