Search Results

Overview

Uniprot ID	Q9UNX4
Protein Name	WD repeat-containing protein 3
Gene Name	WDR3
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
330	KKARKKAKLHSSKGE

Function

Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

Protein Sequence

10 MGLTKQYLRY 20 VASAVFGVIG 30 SQKGNIVFVT 40 LRGEKGRYVA 50 VPACEHVFIW 60 DLRKGEKILI 70 LQGLKQEVTC 80 LCPSPDGLHL 90 AVGYEDGSIR 100 IFSLLSGEGN 110 VTFNGHKAAI 120 TTLKYDQLGG 130 RLASGSKDTD 140 IIVWDVINES 150 GLYRLKGHKD 160 AITQALFLRE 170 KNLLVTSGKD 180 TMVKWWDLDT 190 QHCFKTMVGH 200 RTEVWGLVLL 210 SEEKRLITGA 220 SDSELRVWDI 230 AYLQEIEDPE 240 EPDPKKIKGS 250 SPGIQDTLEA 260 EDGAFETDEA 270 PEDRILSCRK 280 AGSIMREGRD 290 RVVNLAVDKT 300 GRILACHGTD 310 SVLELFCILS 320 KKEIQKKMDK 330 KMKKARKKAK 340 LHSSKGEEED 350 PEVNVEMSLQ 360 DEIQRVTNIK 370 TSAKIKSFDL 380 IHSPHGELKA 390 VFLLQNNLVE 400 LYSLNPSLPT 410 PQPVRTSRIT 420 IGGHRSDVRT 430 LSFSSDNIAV 440 LSAAADSIKI 450 WNRSTLQCIR 460 TMTCEYALCS 470 FFVPGDRQVV 480 IGTKTGKLQL 490 YDLASGNLLE 500 TIDAHDGALW 510 SMSLSPDQRG 520 FVTGGADKSV 530 KFWDFELVKD 540 ENSTQKRLSV 550 KQTRTLQLDE 560 DVLCVSYSPN 570 QKLLAVSLLD 580 CTVKIFYVDT 590 LKFFLSLYGH 600 KLPVICMDIS 610 HDGALIATGS 620 ADRNVKIWGL 630 DFGDCHKSLF 640 AHDDSVMYLQ 650 FVPKSHLFFT 660 AGKDHKIKQW 670 DADKFEHIQT 680 LEGHHQEIWC 690 LAVSPSGDYV 700 VSSSHDKSLR 710 LWERTREPLI 720 LEEEREMERE 730 AEYEESVAKE 740 DQPAVPGETQ 750 GDSYFTGKKT 760 IETVKAAERI 770 MEAIELYREE 780 TAKMKEHKAI 790 CKAAGKEVPL 800 PSNPILMAYG 810 SISPSAYVLE 820 IFKGIKSSEL 830 EESLLVLPFS 840 YVPDILKLFN 850 EFIQLGSDVE 860 LICRCLFFLL 870 RIHFGQITSN 880 QMLVPVIEKL 890 RETTISKVSQ 900 VRDVIGFNMA 910 GLDYLKRECE 920 AKSEVMFFAD 930 ATSHLEEKKR 940 KRKKREKLIL TLT

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005730	nucleolus
Cellular Component	GO:0005654	nucleoplasm
Cellular Component	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome
Cellular Component	GO:0032040	small-subunit processome
Molecular Function	GO:0003723	RNA binding
Molecular Function	GO:0030515	snoRNA binding
Biological Process	GO:0030490	maturation of SSU-rRNA
Biological Process	GO:0042274	ribosomal small subunit biogenesis

Reference

PMID: N/A