Search Results

Overview

Uniprot IDQ9UNZ5
Protein NameLeydig cell tumor 10 kDa protein homolog
Gene NameC19orf53
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
17 AHKPAKSKTAAAASE
48 ARVVQQQKLKKNLEV
50 VVQQQKLKKNLEVGI
51 VQQQKLKKNLEVGIR
7 *MAQGQRKFQAHKPA
76 ASSSLPKKLALLKAP
81 PKKLALLKAPAKKKG
96 AAAATSSKTPS****

Function

May have a potential role in hypercalcemia of malignancy

Protein Sequence

10 MAQGQRKFQA 20 HKPAKSKTAA 30 AASEKNRGPR 40 KGGRVIAPKK 50 ARVVQQQKLK 60 KNLEVGIRKK 70 IEHDVVMKAS 80 SSLPKKLALL 90 KAPAKKKGAA AATSSKTPS

Gene Ontology

No Gene Ontology data available.

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[3] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.

[4] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.