Search Results

Overview

Uniprot IDQ9UQ03
Protein NameCoronin-2B
Gene NameCORO2B
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
23 KFRNVYGKVANREHC
417 KAPIKEKKSVVVNGI

Function

May play a role in the reorganization of neuronal actin structure

Protein Sequence

10 MTVTKMSWRP 20 QYRSSKFRNV 30 YGKVANREHC 40 FDGIPITKNV 50 HDNHFCAVNT 60 RFLAIVTESA 70 GGGSFLVIPL 80 EQTGRIEPNY 90 PKVCGHQGNV 100 LDIKWNPFID 110 NIIASCSEDT 120 SVRIWEIPEG 130 GLKRNMTEAL 140 LELHGHSRRV 150 GLVEWHPTTN 160 NILFSAGYDY 170 KVLIWNLDVG 180 EPVKMIDCHT 190 DVILCMSFNT 200 DGSLLTTTCK 210 DKKLRVIEPR 220 SGRVLQEANC 230 KNHRVNRVVF 240 LGNMKRLLTT 250 GVSRWNTRQI 260 ALWDQEDLSM 270 PLIEEEIDGL 280 SGLLFPFYDA 290 DTHMLYLAGK 300 GDGNIRYYEI 310 STEKPYLSYL 320 MEFRSPAPQK 330 GLGVMPKHGL 340 DVSACEVFRF 350 YKLVTLKGLI 360 EPISMIVPRR 370 SDSYQEDIYP 380 MTPGTEPALT 390 PDEWLGGINR 400 DPVLMSLKEG 410 YKKSSKMVFK 420 APIKEKKSVV 430 VNGIDLLENV 440 PPRTENELLR 450 MFFRQQDEIR 460 RLKEELAQKD 470 IRIRQLQLEL 480 KNLRNSPKNC

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005884 actin filament
Cellular Component GO:0015629 actin cytoskeleton
Cellular Component GO:0005925 focal adhesion
Cellular Component GO:0016020 membrane
Cellular Component GO:0005886 plasma membrane
Molecular Function GO:0003779 actin binding
Molecular Function GO:0051015 actin filament binding
Molecular Function GO:1990147 talin binding
Molecular Function GO:0017166 vinculin binding
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0007015 actin filament organization
Biological Process GO:0048041 focal adhesion assembly
Biological Process GO:0010812 negative regulation of cell-substrate adhesion
Biological Process GO:1904950 negative regulation of establishment of protein localization
Biological Process GO:1904951 positive regulation of establishment of protein localization
Biological Process GO:0032956 regulation of actin cytoskeleton organization
Biological Process GO:0080135 regulation of cellular response to stress

Reference

[1] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.