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Overview

Uniprot IDQ9WV03
Protein NameProtein FAM50A
Gene NameFam50a
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
5 ***MAQYKGAASEAG

Function

Probably involved in the regulation of pre-mRNA splicing

Protein Sequence

10 MAQYKGAASE 20 AGRAMHLMKK 30 REKQREQMEQ 40 MKQRIAEENI 50 MKSNIDKKFS 60 AHYDAVEAEL 70 KSSTVGLVTL 80 NDMKAKQEAL 90 VKEREKQLAK 100 KEQSKELQLK 110 LEKLREKERK 120 KEAKRKISSL 130 SFTLEEEEEG 140 VEEEEEMAMY 150 EEELEREEIT 160 TKKKKLGKNP 170 DVDTSFLPDR 180 DREEEENRLR 190 EELRQEWEAK 200 QEKIKSEEIE 210 ITFSYWDGSG 220 HRRTVKMKKG 230 NTMQQFLQKA 240 LEILRKDFSE 250 LRSAGVEQLM 260 YIKEDLIIPH 270 HHSFYDFIVT 280 KARGKSGPLF 290 NFDVHDDVRL 300 LSDATVEKDE 310 SHAGKVVLRS 320 WYEKNKHIFP 330 ASRWEPYDPE KKWDKYTIR

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Biological Process GO:0006325 chromatin organization
Biological Process GO:0006397 mRNA processing
Biological Process GO:0043484 regulation of RNA splicing
Biological Process GO:0008380 RNA splicing

Reference

[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.

[2] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.