Search Results
Overview
| Uniprot ID | Q9Y285 |
|---|---|
| Protein Name | Phenylalanine--tRNA ligase alpha subunit |
| Gene Name | FARSA |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 117 | NKWIRVDKSAADGPR |
Function
No function data available.
Protein Sequence
10
MADGQVAELL
20
LRRLEASDGG
30
LDSAELAAEL
40
GMEHQAVVGA
50
VKSLQALGEV
60
IEAELRSTKH
70
WELTAEGEEI
80
AREGSHEARV
90
FRSIPPEGLA
100
QSELMRLPSG
110
KVGFSKAMSN
120
KWIRVDKSAA
130
DGPRVFRVVD
140
SMEDEVQRRL
150
QLVRGGQAEK
160
LGEKERSELR
170
KRKLLAEVTL
180
KTYWVSKGSA
190
FSTSISKQET
200
ELSPEMISSG
210
SWRDRPFKPY
220
NFLAHGVLPD
230
SGHLHPLLKV
240
RSQFRQIFLE
250
MGFTEMPTDN
260
FIESSFWNFD
270
ALFQPQQHPA
280
RDQHDTFFLR
290
DPAEALQLPM
300
DYVQRVKRTH
310
SQGGYGSQGY
320
KYNWKLDEAR
330
KNLLRTHTTS
340
ASARALYRLA
350
QKKPFTPVKY
360
FSIDRVFRNE
370
TLDATHLAEF
380
HQIEGVVADH
390
GLTLGHLMGV
400
LREFFTKLGI
410
TQLRFKPAYN
420
PYTEPSMEVF
430
SYHQGLKKWV
440
EVGNSGVFRP
450
EMLLPMGLPE
460
NVSVIAWGLS
470
LERPTMIKYG
480
INNIRELVGH
490
KVNLQMVYDS
500
PLCRLDAEPR
PPPTQEAA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0009328 | phenylalanine-tRNA ligase complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0000287 | magnesium ion binding |
| Molecular Function | GO:0004826 | phenylalanine-tRNA ligase activity |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0000049 | tRNA binding |
| Biological Process | GO:0006432 | phenylalanyl-tRNA aminoacylation |
| Biological Process | GO:0051290 | protein heterotetramerization |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.
[2] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.