Search Results
Overview
| Uniprot ID | Q9Y2C4 |
|---|---|
| Protein Name | Nuclease EXOG, mitochondrial |
| Gene Name | EXOG |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 355 | EKKLEELKAKEQSGT |
Function
Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity
Protein Sequence
10
MAIKSIASRL
20
RGSRRFLSGF
30
VAGAVVGAAG
40
AGLAALQFFR
50
SQGAEGALTG
60
KQPDGSAEKA
70
VLEQFGFPLT
80
GTEARCYTNH
90
ALSYDQAKRV
100
PRWVLEHISK
110
SKIMGDADRK
120
HCKFKPDPNI
130
PPTFSAFNED
140
YVGSGWSRGH
150
MAPAGNNKFS
160
SKAMAETFYL
170
SNIVPQDFDN
180
NSGYWNRIEM
190
YCRELTERFE
200
DVWVVSGPLT
210
LPQTRGDGKK
220
IVSYQVIGED
230
NVAVPSHLYK
240
VILARRSSVS
250
TEPLALGAFV
260
VPNEAIGFQP
270
QLTEFQVSLQ
280
DLEKLSGLVF
290
FPHLDRTSDI
300
RNICSVDTCK
310
LLDFQEFTLY
320
LSTRKIEGAR
330
SVLRLEKIME
340
NLKNAEIEPD
350
DYFMSRYEKK
360
LEELKAKEQS
GTQIRKPS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0032991 | protein-containing complex |
| Molecular Function | GO:0008409 | 5'-3' exonuclease activity |
| Molecular Function | GO:0004519 | endonuclease activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0003676 | nucleic acid binding |
| Molecular Function | GO:0004521 | RNA endonuclease activity |
| Molecular Function | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity |
| Biological Process | GO:0006309 | apoptotic DNA fragmentation |
Reference
PMID: N/A