Search Results
Overview
| Uniprot ID | Q9Y2I8 |
|---|---|
| Protein Name | WD repeat-containing protein 37 |
| Gene Name | WDR37 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 132 | TYKASTSKIVSSFKT |
| 396 | TVKVWDLKNMRSPIA |
| 421 | INVCVGQKIIALPHD |
Function
Required for normal ER Ca2+ handling in lymphocytes. Together with PACS1, it plays an essential role in stabilizing peripheral lymphocyte populations
Protein Sequence
10
MPTESASCST
20
ARQTKQKRKS
30
HSLSIRRTNS
40
SEQERTGLPR
50
DMLEGQDSKL
60
PSSVRSTLLE
70
LFGQIEREFE
80
NLYIENLELR
90
REIDTLNERL
100
AAEGQAIDGA
110
ELSKGQLKTK
120
ASHSTSQLSQ
130
KLKTTYKAST
140
SKIVSSFKTT
150
TSRAACQLVK
160
EYIGHRDGIW
170
DVSVAKTQPV
180
VLGTASADHT
190
ALLWSIETGK
200
CLVKYAGHVG
210
SVNSIKFHPS
220
EQLALTASGD
230
QTAHIWRYAV
240
QLPTPQPVAD
250
TSISGEDEVE
260
CSDKDEPDLD
270
GDVSSDCPTI
280
RVPLTSLKSH
290
QGVVIASDWL
300
VGGKQAVTAS
310
WDRTANLYDV
320
ETSELVHSLT
330
GHDQELTHCC
340
THPTQRLVVT
350
SSRDTTFRLW
360
DFRDPSIHSV
370
NVFQGHTDTV
380
TSAVFTVGDN
390
VVSGSDDRTV
400
KVWDLKNMRS
410
PIATIRTDSA
420
INRINVCVGQ
430
KIIALPHDNR
440
QVRLFDMSGV
450
RLARLPRSSR
460
QGHRRMVCCS
470
AWSEDHPVCN
480
LFTCGFDRQA
490
IGWNINIPAL
LQEK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Biological Process | GO:0002260 | lymphocyte homeostasis |
Reference
[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.
[2] Shi CM, Wang QC, Li XL, Yang YH, Tang XY et al.. Global Profiling of Protein Lactylation in Human Hippocampi.. Proteomics Clin Appl 19(2):e202400061. 2025 Mar. PMID: 39610256.
[3] Chao L, Xu Y, Yang Y, Ao X, Liang J. Identification of lactylation-related biomarkers for diagnosis, prognosis, and treatment responsiveness in triple-negative breast cancer.. World J Surg Oncol 24(1):77. 2026 Jan 22. PMID: 41566505.