Search Results

Overview

Uniprot ID	Q9Y2V7
Protein Name	Conserved oligomeric Golgi complex subunit 6
Gene Name	COG6
Organism	Homo sapiens

Kla Sites from experimental identification

Position	Flanking peptide
51	ETRLDNDKEMLEALK

Function

Required for normal Golgi function

Protein Sequence

10 MAEGSGEVVA 20 VSATGAANGL 30 NNGAGGTSAT 40 TCNPLSRKLH 50 KILETRLDND 60 KEMLEALKAL 70 STFFVENSLR 80 TRRNLRGDIE 90 RKSLAINEEF 100 VSIFKEVKEE 110 LESISEDVQA 120 MSNCCQDMTS 130 RLQAAKEQTQ 140 DLIVKTTKLQ 150 SESQKLEIRA 160 QVADAFLSKF 170 QLTSDEMSLL 180 RGTREGPITE 190 DFFKALGRVK 200 QIHNDVKVLL 210 RTNQQTAGLE 220 IMEQMALLQE 230 TAYERLYRWA 240 QSECRTLTQE 250 SCDVSPVLTQ 260 AMEALQDRPV 270 LYKYTLDEFG 280 TARRSTVVRG 290 FIDALTRGGP 300 GGTPRPIEMH 310 SHDPLRYVGD 320 MLAWLHQATA 330 SEKEHLEALL 340 KHVTTQGVEE 350 NIQEVVGHIT 360 EGVCRPLKVR 370 IEQVIVAEPG 380 AVLLYKISNL 390 LKFYHHTISG 400 IVGNSATALL 410 TTIEEMHLLS 420 KKIFFNSLSL 430 HASKLMDKVE 440 LPPPDLGPSS 450 ALNQTLMLLR 460 EVLASHDSSV 470 VPLDARQADF 480 VQVLSCVLDP 490 LLQMCTVSAS 500 NLGTADMATF 510 MVNSLYMMKT 520 TLALFEFTDR 530 RLEMLQFQIE 540 AHLDTLINEQ 550 ASYVLTRVGL 560 SYIYNTVQQH 570 KPEQGSLANM 580 PNLDSVTLKA 590 AMVQFDRYLS 600 APDNLLIPQL 610 NFLLSATVKE 620 QIVKQSTELV 630 CRAYGEVYAA 640 VMNPINEYKD 650 PENILHRSPQ QVQTLLS

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0000139	Golgi membrane
Cellular Component	GO:0017119	Golgi transport complex
Cellular Component	GO:0032588	trans-Golgi network membrane
Biological Process	GO:0007030	Golgi organization
Biological Process	GO:0006891	intra-Golgi vesicle-mediated transport
Biological Process	GO:0015031	protein transport
Biological Process	GO:0000301	retrograde transport, vesicle recycling within Golgi

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.