Search Results

Overview

Uniprot IDQ9Y366
Protein NameIntraflagellar transport protein 52 homolog
Gene NameIFT52
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
26 FTTNNGYKSMQKKLR
31 GYKSMQKKLRSNWKI

Function

Involved in ciliogenesis as part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia (PubMed:27466190). Required for the anterograde transport of IFT88 (PubMed:27466190)

Protein Sequence

10 MEKELRSTIL 20 FNAYKKEIFT 30 TNNGYKSMQK 40 KLRSNWKIQS 50 LKDEITSEKL 60 NGVKLWITAG 70 PREKFTAAEF 80 EILKKYLDTG 90 GDVFVMLGEG 100 GESRFDTNIN 110 FLLEEYGIMV 120 NNDAVVRNVY 130 HKYFHPKEAL 140 VSSGVLNREI 150 SRAAGKAVPG 160 IIDEESSGNN 170 AQALTFVYPF 180 GATLSVMKPA 190 VAVLSTGSVC 200 FPLNRPILAF 210 YHSKNQGGKL 220 AVLGSCHMFS 230 DQYLDKEENS 240 KIMDVVFQWL 250 TTGDIHLNQI 260 DAEDPEISDY 270 MMLPYTATLS 280 KRNRECLQES 290 DEIPRDFTTL 300 FDLSIFQLDT 310 TSFHSVIEAH 320 EQLNVKHEPL 330 QLIQPQFETP 340 LPTLQPAVFP 350 PSFRELPPPP 360 LELFDLDETF 370 SSEKARLAQI 380 TNKCTEEDLE 390 FYVRKCGDIL 400 GVTSKLPKDQ 410 QDAKHILEHV 420 FFQVVEFKKL 430 NQEHDIDTSE TAFQNNF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005814 centriole
Cellular Component GO:0005813 centrosome
Cellular Component GO:0036064 ciliary basal body
Cellular Component GO:0097546 ciliary base
Cellular Component GO:0097542 ciliary tip
Cellular Component GO:0005929 cilium
Cellular Component GO:0044292 dendrite terminus
Cellular Component GO:0030991 intraciliary transport particle A
Cellular Component GO:0030992 intraciliary transport particle B
Cellular Component GO:0031514 motile cilium
Cellular Component GO:0032391 photoreceptor connecting cilium
Biological Process GO:0060271 cilium assembly
Biological Process GO:0035720 intraciliary anterograde transport
Biological Process GO:0042073 intraciliary transport

Reference

[1] Cheng Z, Huang H, Li M, Chen Y. Proteomic analysis identifies PFKP lactylation in SW480 colon cancer cells.. iScience 27(1):108645. 2024 Jan 19. PMID: 38155775.