Search Results
Overview
| Uniprot ID | Q9Y3A2 |
|---|---|
| Protein Name | Probable U3 small nucleolar RNA-associated protein 11 |
| Gene Name | UTP11 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 26 | RSQPGFRKHLGLLEK |
Function
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA
Protein Sequence
10
MAAAFRKAAK
20
SRQREHRERS
30
QPGFRKHLGL
40
LEKKKDYKLR
50
ADDYRKKQEY
60
LKALRKKALE
70
KNPDEFYYKM
80
TRVKLQDGVH
90
IIKETKEEVT
100
PEQLKLMRTQ
110
DVKYIEMKRV
120
AEAKKIERLK
130
SELHLLDFQG
140
KQQNKHVFFF
150
DTKKEVEQFD
160
VATHLQTAPE
170
LVDRVFNRPR
180
IETLQKEKVK
190
GVTNQTGLKR
200
IAKERQKQYN
210
CLTQRIEREK
220
KLFVIAQKIQ
230
TRKDLMDKTQ
240
KVKVKKETVN
250
SPAIYKFQSR
RKR
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0032040 | small-subunit processome |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0030490 | maturation of SSU-rRNA |
| Biological Process | GO:0007399 | nervous system development |
| Biological Process | GO:0043065 | positive regulation of apoptotic process |
| Biological Process | GO:0042274 | ribosomal small subunit biogenesis |
Reference
PMID: N/A