Search Results

Overview

Uniprot IDQ9Y3B9
Protein NameRRP15-like protein
Gene NameRRP15
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
114 SKPTILVKNKKLEKE
132 LKQERLEKIKQRDKR
134 QERLEKIKQRDKRLE
17 VSEEENLKKTPKKKM
179 QLFNAVQKHQKNVDE
18 SEEENLKKTPKKKMK
200 SSMRKRAKLISTVSK
207 KLISTVSKKDFISVL
208 LISTVSKKDFISVLR

Function

No function data available.

Protein Sequence

10 MAAAAPDSRV 20 SEEENLKKTP 30 KKKMKMVTGA 40 VASVLEDEAT 50 DTSDSEGSCG 60 SEKDHFYSDD 70 DAIEADSEGD 80 AEPCDKENEN 90 DGESSVGTNM 100 GWADAMAKVL 110 NKKTPESKPT 120 ILVKNKKLEK 130 EKEKLKQERL 140 EKIKQRDKRL 150 EWEMMCRVKP 160 DVVQDKETER 170 NLQRIATRGV 180 VQLFNAVQKH 190 QKNVDEKVKE 200 AGSSMRKRAK 210 LISTVSKKDF 220 ISVLRGMDGS 230 TNETASSRKK 240 PKAKQTEVKS 250 EEGPGWTILR 260 DDFMMGASMK 270 DWDKESDGPD 280 DSRPESASDS DT

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030687 preribosome, large subunit precursor
Biological Process GO:0000460 maturation of 5.8S rRNA
Biological Process GO:0000470 maturation of LSU-rRNA

Reference

[1] Yang D, Yin J, Shan L, Yi X, Zhang W et al.. Identification of lysine-lactylated substrates in gastric cancer cells.. iScience 25(7):104630. 2022 Jul 15. PMID: 35800753.

[2] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[3] Lin Y, Chen M, Wang D, Yu Y, Chen R et al.. Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.. J Proteome Res 22(6):1712-1722. 2023 Jun 2. PMID: 37159428.

[4] He C, Zhang J, Bai X, Lu C, Zhang K. Lysine lactylation-based insight to understanding the characterization of cervical cancer.. Biochim Biophys Acta Mol Basis Dis 1870(7):167356. 2024 Oct. PMID: 39025375.

[5] Bao Q, Wan N, He Z, Cao J, Yuan W et al.. Subcellular Proteomic Mapping of Lysine Lactylation.. J Am Soc Mass Spectrom 35(12):3221-3232. 2024 Dec 4. PMID: 39569522.

[6] He J, Lai T, Zhou Z, Yang H, Lei Z et al.. Multiomics profiling reveals the involvement of protein lactylation in nonhomologous end joining pathway conferring radioresistance in lung adenocarcinoma cell.. Sci Rep 15(1):24651. 2025 Jul 9. PMID: 40634431.

[7] Wu Q, Li Z, Gong T, Zheng X, Zhou X et al.. Porphyromonas gingivalis infection induces lysine lactylation reprogramming in human umbilical vein endothelial cells.. Front Cell Infect Microbiol 16:1706727. 2026. PMID: 41696360.