Search Results

Overview

Uniprot IDQ9Y4P3
Protein NameTransducin beta-like protein 2
Gene NameTBL2
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
262 VWEVCFGKKGEFQEV
446 LKSLGALKK******

Function

No function data available.

Protein Sequence

10 MELSQMSELM 20 GLSVLLGLLA 30 LMATAAVARG 40 WLRAGEERSG 50 RPACQKANGF 60 PPDKSSGSKK 70 QKQYQRIRKE 80 KPQQHNFTHR 90 LLAAALKSHS 100 GNISCMDFSS 110 NGKYLATCAD 120 DRTIRIWSTK 130 DFLQREHRSM 140 RANVELDHAT 150 LVRFSPDCRA 160 FIVWLANGDT 170 LRVFKMTKRE 180 DGGYTFTATP 190 EDFPKKHKAP 200 VIDIGIANTG 210 KFIMTASSDT 220 TVLIWSLKGQ 230 VLSTINTNQM 240 NNTHAAVSPC 250 GRFVASCGFT 260 PDVKVWEVCF 270 GKKGEFQEVV 280 RAFELKGHSA 290 AVHSFAFSND 300 SRRMASVSKD 310 GTWKLWDTDV 320 EYKKKQDPYL 330 LKTGRFEEAA 340 GAAPCRLALS 350 PNAQVLALAS 360 GSSIHLYNTR 370 RGEKEECFER 380 VHGECIANLS 390 FDITGRFLAS 400 CGDRAVRLFH 410 NTPGHRAMVE 420 EMQGHLKRAS 430 NESTRQRLQQ 440 QLTQAQETLK SLGALKK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0005789 endoplasmic reticulum membrane
Molecular Function GO:0051219 phosphoprotein binding
Molecular Function GO:0019901 protein kinase binding
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0031369 translation initiation factor binding
Biological Process GO:0042149 cellular response to glucose starvation
Biological Process GO:0071456 cellular response to hypoxia
Biological Process GO:0030968 endoplasmic reticulum unfolded protein response

Reference

[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.

[2] Hong H, Chen X, Wang H, Gu X, Yuan Y et al.. Global profiling of protein lysine lactylation and potential target modified protein analysis in hepatocellular carcinoma.. Proteomics 23(9):e2200432. 2023 May. PMID: 36625413.