Search Results
Overview
| Uniprot ID | Q9Y5M8 |
|---|---|
| Protein Name | Signal recognition particle receptor subunit beta |
| Gene Name | SRPRB |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 227 | TAPAQLGKKGKEFEF |
Function
Component of the signal recognition particle (SRP) complex receptor (SR) (By similarity). Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system (By similarity). May mediate the membrane association of SR (By similarity)
Protein Sequence
10
MASADSRRVA
20
DGGGAGGTFQ
30
PYLDTLRQEL
40
QQTDPTLLSV
50
VVAVLAVLLT
60
LVFWKLIRSR
70
RSSQRAVLLV
80
GLCDSGKTLL
90
FVRLLTGLYR
100
DTQTSITDSC
110
AVYRVNNNRG
120
NSLTLIDLPG
130
HESLRLQFLE
140
RFKSSARAIV
150
FVVDSAAFQR
160
EVKDVAEFLY
170
QVLIDSMGLK
180
NTPSFLIACN
190
KQDIAMAKSA
200
KLIQQQLEKE
210
LNTLRVTRSA
220
APSTLDSSST
230
APAQLGKKGK
240
EFEFSQLPLK
250
VEFLECSAKG
260
GRGDVGSADI
270
QDLEKWLAKI
A
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005881 | cytoplasmic microtubule |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005785 | signal recognition particle receptor complex |
| Molecular Function | GO:0005525 | GTP binding |
| Biological Process | GO:0045047 | protein targeting to ER |
| Biological Process | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.