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Overview

Uniprot IDQ9Y5Q8
Protein NameGeneral transcription factor 3C polypeptide 5
Gene NameGTF3C5
OrganismHomo sapiens

Kla Sites from experimental identification

Position Flanking peptide
339 APSDLPVKAKRSTYN

Function

Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters

Protein Sequence

10 MAAEAADLGL 20 GAAVPVELRR 30 ERRMVCVEYP 40 GVVRDVAKML 50 PTLGGEEGVS 60 RIYADPTKRL 70 ELYFRPKDPY 80 CHPVCANRFS 90 TSSLLLRIRK 100 RTRRQKGVLG 110 TEAHSEVTFD 120 MEILGIISTI 130 YKFQGMSDFQ 140 YLAVHTEAGG 150 KHTSMYDKVL 160 MLRPEKEAFF 170 HQELPLYIPP 180 PIFSRLDAPV 190 DYFYRPETQH 200 REGYNNPPIS 210 GENLIGLSRA 220 RRPHNAIFVN 230 FEDEEVPKQP 240 LEAAAQTWRR 250 VCTNPVDRKV 260 EEELRKLFDI 270 RPIWSRNAVK 280 ANISVHPDKL 290 KVLLPFIAYY 300 MITGPWRSLW 310 IRFGYDPRKN 320 PDAKIYQVLD 330 FRIRCGMKHG 340 YAPSDLPVKA 350 KRSTYNYSLP 360 ITVKKTSSQL 370 VTMHDLKQGL 380 GPSGTSGARK 390 PASSKYKLKD 400 SVYIFREGAL 410 PPYRQMFYQL 420 CDLNVEELQK 430 IIHRNDGAEN 440 SCTERDGWCL 450 PKTSDELRDT 460 MSLMIRQTIR 470 SKRPALFSSS 480 AKADGGKEQL 490 TYESGEDEED 500 EEEEEEEEED 510 FKPSDGSENE METEILDYV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0000127 transcription factor TFIIIC complex
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0000995 RNA polymerase III general transcription initiation factor activity
Biological Process GO:0042791 5S class rRNA transcription by RNA polymerase III
Biological Process GO:0006383 transcription by RNA polymerase III
Biological Process GO:0006384 transcription initiation at RNA polymerase III promoter
Biological Process GO:0042797 tRNA transcription by RNA polymerase III

Reference

PMID: N/A