Search Results
Overview
| Uniprot ID | Q9Y5Z4 |
|---|---|
| Protein Name | Heme-binding protein 2 |
| Gene Name | HEBP2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 184 | AGYNSPVKLLNRNNE |
Function
Can promote mitochondrial permeability transition and facilitate necrotic cell death under different types of stress conditions
Protein Sequence
10
MAEPLQPDPG
20
AAEDAAAQAV
30
ETPGWKAPED
40
AGPQPGSYEI
50
RHYGPAKWVS
60
TSVESMDWDS
70
AIQTGFTKLN
80
SYIQGKNEKE
90
MKIKMTAPVT
100
SYVEPGSGPF
110
SESTITISLY
120
IPSEQQFDPP
130
RPLESDVFIE
140
DRAEMTVFVR
150
SFDGFSSAQK
160
NQEQLLTLAS
170
ILREDGKVFD
180
EKVYYTAGYN
190
SPVKLLNRNN
200
EVWLIQKNEP
TKENE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0035578 | azurophil granule lumen |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005576 | extracellular region |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0020037 | heme binding |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.