Search Results
Overview
| Uniprot ID | Q9Y6W3 |
|---|---|
| Protein Name | Calpain-7 |
| Gene Name | CAPN7 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 160 | PLTKPVGKISSTSVK |
Function
Calcium-regulated non-lysosomal thiol-protease
Protein Sequence
10
MDATALERDA
20
VQFARLAVQR
30
DHEGRYSEAV
40
FYYKEAAQAL
50
IYAEMAGSSL
60
ENIQEKITEY
70
LERVQALHSA
80
VQSKSADPLK
90
SKHQLDLERA
100
HFLVTQAFDE
110
DEKENVEDAI
120
ELYTEAVDLC
130
LKTSYETADK
140
VLQNKLKQLA
150
RQALDRAEAL
160
SEPLTKPVGK
170
ISSTSVKPKP
180
PPVRAHFPLG
190
ANPFLERPQS
200
FISPQSCDAQ
210
GQRYTAEEIE
220
VLRTTSKING
230
IEYVPFMNVD
240
LRERFAYPMP
250
FCDRWGKLPL
260
SPKQKTTFSK
270
WVRPEDLTNN
280
PTMIYTVSSF
290
SIKQTIVSDC
300
SFVASLAISA
310
AYERRFNKKL
320
ITGIIYPQNK
330
DGEPEYNPCG
340
KYMVKLHLNG
350
VPRKVIIDDQ
360
LPVDHKGELL
370
CSYSNNKSEL
380
WVSLIEKAYM
390
KVMGGYDFPG
400
SNSNIDLHAL
410
TGWIPERIAM
420
HSDSQTFSKD
430
NSFRMLYQRF
440
HKGDVLITAS
450
TGMMTEAEGE
460
KWGLVPTHAY
470
AVLDIREFKG
480
LRFIQLKNPW
490
SHLRWKGRYS
500
ENDVKNWTPE
510
LQKYLNFDPR
520
TAQKIDNGIF
530
WISWDDLCQY
540
YDVIYLSWNP
550
GLFKESTCIH
560
STWDAKQGPV
570
KDAYSLANNP
580
QYKLEVQCPQ
590
GGAAVWVLLS
600
RHITDKDDFA
610
NNREFITMVV
620
YKTDGKKVYY
630
PADPPPYIDG
640
IRINSPHYLT
650
KIKLTTPGTH
660
TFTLVVSQYE
670
KQNTIHYTVR
680
VYSACSFTFS
690
KIPSPYTLSK
700
RINGKWSGQS
710
AGGCGNFQET
720
HKNNPIYQFH
730
IEKTGPLLIE
740
LRGPRQYSVG
750
FEVVTVSTLG
760
DPGPHGFLRK
770
SSGDYRCGFC
780
YLELENIPSG
790
IFNIIPSTFL
800
PKQEGPFFLD
810
FNSIIPIKIT
QLQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0070062 | extracellular exosome |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity |
| Molecular Function | GO:0004197 | cysteine-type endopeptidase activity |
| Molecular Function | GO:0004175 | endopeptidase activity |
| Molecular Function | GO:0090541 | MIT domain binding |
| Biological Process | GO:0010634 | positive regulation of epithelial cell migration |
| Biological Process | GO:0006508 | proteolysis |
| Biological Process | GO:0097264 | self proteolysis |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.