Search Results
Overview
| Uniprot ID | Q9Y6Y8 |
|---|---|
| Protein Name | SEC23-interacting protein |
| Gene Name | SEC23IP |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 733 | EQSAQKTKDMASLPS |
Function
Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P)
Protein Sequence
10
MAERKPNGGS
20
GGASTSSSGT
30
NLLFSSSATE
40
FSFNVPFIPV
50
TQASASPASL
60
LLPGEDSTDV
70
GEEDSFLGQT
80
SIHTSAPQTF
90
SYFSQVSSSS
100
DPFGNIGQSP
110
LTTAATSVGQ
120
SGFPKPLTAL
130
PFTTGSQDVS
140
NAFSPSISKA
150
QPGAPPSSLM
160
GINSYLPSQP
170
SSLPPSYFGN
180
QPQGIPQPGY
190
NPYRHTPGSS
200
RANPYIAPPQ
210
LQQCQTPGPP
220
AHPPPSGPPV
230
QMYQMPPGSL
240
PPVPSSVQSP
250
AQQQVPARPG
260
APSVQVPSPF
270
LLQNQYEPVQ
280
PHWFYCKEVE
290
YKQLWMPFSV
300
FDSLNLEEIY
310
NSVQPDPESV
320
VLGTDGGRYD
330
VYLYDRIRKA
340
AYWEEEPAEV
350
RRCTWFYKGD
360
TDSRFIPYTE
370
EFSEKLEAEY
380
KKAVTTNQWH
390
RRLEFPSGET
400
IVMHNPKVIV
410
QFQPSSVPDE
420
WGTTQDGQTR
430
PRVVKRGIDD
440
NLDEIPDGEM
450
PQVDHLVFVV
460
HGIGPVCDLR
470
FRSIIECVDD
480
FRVVSLKLLR
490
THFKKSLDDG
500
KVSRVEFLPV
510
HWHSSLGGDA
520
TGVDRNIKKI
530
TLPSIGRFRH
540
FTNETLLDIL
550
FYNSPTYCQT
560
IVEKVGMEIN
570
HLHALFMSRN
580
PDFKGGVSVA
590
GHSLGSLILF
600
DILSNQKDLN
610
LSKCPGPLAV
620
ANGVVKQLHF
630
QEKQMPEEPK
640
LTLDESYDLV
650
VENKEVLTLQ
660
ETLEALSLSE
670
YFSTFEKEKI
680
DMESLLMCTV
690
DDLKEMGIPL
700
GPRKKIANFV
710
EHKAAKLKKA
720
ASEKKAVAAT
730
STKGQEQSAQ
740
KTKDMASLPS
750
ESNEPKRKLP
760
VGACVSSVCV
770
NYESFEVGAG
780
QVSVAYNSLD
790
FEPEIFFALG
800
SPIAMFLTIR
810
GVDRIDENYS
820
LPTCKGFFNI
830
YHPLDPVAYR
840
LEPMIVPDLD
850
LKAVLIPHHK
860
GRKRLHLELK
870
ESLSRMGSDL
880
KQGFISSLKS
890
AWQTLNEFAR
900
AHTSSTQLQE
910
ELEKVANQIK
920
EEEEKQVVEA
930
EKVVESPDFS
940
KDEDYLGKVG
950
MLNGGRRIDY
960
VLQEKPIESF
970
NEYLFALQSH
980
LCYWESEDTA
990
LLLLKEIYRT
1000
MNISPEQPQH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030134 | COPII-coated ER to Golgi transport vesicle |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment |
| Cellular Component | GO:0012507 | ER to Golgi transport vesicle membrane |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Molecular Function | GO:0004620 | glycerophospholipase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport |
| Biological Process | GO:0007030 | Golgi organization |
| Biological Process | GO:0006886 | intracellular protein transport |
| Biological Process | GO:0007286 | spermatid development |
Reference
[1] Yang Z, Yan C, Ma J, Peng P, Ren X et al.. Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.. Nat Metab 5(1):61-79. 2023 Jan. PMID: 36593272.