Search Results

Overview

Uniprot IDQ9Z1P6
Protein NameNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Gene NameNdufa7
OrganismMus musculus

Kla Sites from experimental identification

Position Flanking peptide
102 VTPAPPMKRWELSKD
40 KRTQPPPKLPVGPSH
80 QKALVSGKAAESSAM
92 SAMAATEKKAVTPAP
93 AMAATEKKAVTPAPP

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Protein Sequence

10 MASATRVIQK 20 LRNWASGQDL 30 QAKLQLRYQE 40 IAKRTQPPPK 50 LPVGPSHKLS 60 NNYYCTRDGR 70 REVVPPSIIM 80 SSQKALVSGK 90 AAESSAMAAT 100 EKKAVTPAPP 110 MKRWELSKDQ PYL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0045271 respiratory chain complex I
Biological Process GO:0009060 aerobic respiration
Biological Process GO:0006120 mitochondrial electron transport, NADH to ubiquinone
Biological Process GO:0042776 proton motive force-driven mitochondrial ATP synthesis

Reference

[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.

[2] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.

[3] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.