Search Results
Overview
| Uniprot ID | Q9Z2X1 |
|---|---|
| Protein Name | Heterogeneous nuclear ribonucleoprotein F |
| Gene Name | Hnrnpf |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 224 | RRYIGIVKQAGLDRM |
Function
Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state (By similarity)
Protein Sequence
10
MMLGPEGGEG
20
YVVKLRGLPW
30
SCSIEDVQNF
40
LSDCTIHDGV
50
AGVHFIYTRE
60
GRQSGEAFVE
70
LESEDDVKLA
80
LKKDRESMGH
90
RYIEVFKSHR
100
TEMDWVLKHS
110
GPNSADSAND
120
GFVRLRGLPF
130
GCTKEEIVQF
140
FSGLEIVPNG
150
ITLPVDPEGK
160
ITGEAFVQFA
170
SQELAEKALG
180
KHKERIGHRY
190
IEVFKSSQEE
200
VRSYSDPPLK
210
FMSVQRPGPY
220
DRPGTARRYI
230
GIVKQAGLDR
240
MRSGAYSAGY
250
GGYEEYSGLS
260
DGYGFTTDLF
270
GRDLSYCLSG
280
MYDHRYGDSE
290
FTVQSTTGHC
300
VHMRGLPYKA
310
TENDIYNFFS
320
PLNPVRVHIE
330
IGPDGRVTGE
340
ADVEFATHEE
350
AVAAMSKDRA
360
NMQHRYIELF
370
LNSTTGASNG
380
AYSSQVMQGM
390
GVSAAQATYS
400
GLESQSVSGC
410
YGAGYSGQNS
MGGYD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Cellular Component | GO:0045202 | synapse |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0003727 | single-stranded RNA binding |
| Molecular Function | GO:0017025 | TBP-class protein binding |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0043484 | regulation of RNA splicing |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.