Search Results
Overview
| Uniprot ID | Q9Z2Y8 |
|---|---|
| Protein Name | Pyridoxal phosphate homeostasis protein |
| Gene Name | Plpbp |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 132 | KVNSSWQKKGPTEPL |
| 49 | LVAVSKTKPADMVIE |
| 81 | LEKASNPKILSSCPE |
| 99 | HFIGHLQKQNVNKLM |
Function
Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6
Protein Sequence
10
MLRGGSMTAE
20
LGVGFALRAV
30
NERVQQSVAR
40
RPRDLPAIQP
50
RLVAVSKTKP
60
ADMVIEAYGH
70
GQRTFGENYV
80
QELLEKASNP
90
KILSSCPEIK
100
WHFIGHLQKQ
110
NVNKLMAVPN
120
LSMLETVDSV
130
KLADKVNSSW
140
QKKGPTEPLK
150
VMVQINTSGE
160
DSKHGLLPSE
170
TIAVVEHIKA
180
SCPSLEFVGL
190
MTIGSFGHDL
200
SQGPNPDFQR
210
LLTLRRELCE
220
KLGIPVEQVE
230
LSMGMSMDFQ
240
HAIEVGSTNV
250
RIGSTIFGER
260
DYSKKPALDK
270
TADAKASVPL
VQGH
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0030170 | pyridoxal phosphate binding |
| Biological Process | GO:0042816 | vitamin B6 metabolic process |
Reference
[1] Zhuo W, Zhang M, Tan J, Gao Y, Wang Y et al.. Lysine lactylation analysis of proteins in the heart of the Kawasaki disease mouse model.. Front Cell Dev Biol 13:1550220. 2025. PMID: 40114965.
[2] Wu D, Tang Y, Li X, Xiong S, Zhang Z et al.. Characterization of protein lactylation in healthy and ischemic mouse hearts.. Front Cardiovasc Med 12:1644886. 2025. PMID: 41089239.