Search Results
Overview
| Uniprot ID | R4SBI6 |
|---|---|
| Protein Name | Epoxide hydrolase |
| Gene Name | EPHX1 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 168 | IPLLTDPKNHGLSDE |
| 196 | GFSEASSKKGFNSVA |
| 306 | YMHIQCTKPDTVGSA |
Function
Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water
Protein Sequence
10
MWLEILLTSV
20
LGFAIYWFIS
30
RDKEETLPLE
40
DGWWGPGTRS
50
AAREDDSIRP
60
FKVETSDEEI
70
HDLHQRIDKF
80
RFTPPLEDSC
90
FHYGFNSNYL
100
KKVISYWRNE
110
FDWKKQVEIL
120
NRYPHFKTKI
130
EGLDIHFIHV
140
KPPQLPAGHT
150
PKPLLMVHGW
160
PGSFYEFYKI
170
IPLLTDPKNH
180
GLSDEHVFEV
190
ICPSIPGYGF
200
SEASSKKGFN
210
SVATARIFYK
220
LMLRLGFQEF
230
YIQGGDWGSL
240
ICTNMAQLVP
250
SHVKGLHLNM
260
ALVLSNFSTL
270
TLLLGQRFGR
280
FLGLTERDVE
290
LLYPVKEKVF
300
YSLMRESGYM
310
HIQCTKPDTV
320
GSALNDSPVG
330
LAAYILEKFS
340
TWTNTEFRYL
350
EDGGLERKFS
360
LDDLLTNVML
370
YWTTGTIISS
380
QRFYKENLGQ
390
GWMTQKHERM
400
KVYVPTGFSA
410
FPFELLHTPE
420
KWVRFKYPKL
430
ISYSYMVRGG
440
HFAAFEEPEL
450
LAQDIRKFLS
VLERQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Molecular Function | GO:0033961 | cis-stilbene-oxide hydrolase activity |
| Molecular Function | GO:0008142 | oxysterol binding |
| Biological Process | GO:0006629 | lipid metabolic process |
| Biological Process | GO:0009636 | response to toxic substance |
Reference
PMID: N/A