Search Results
Overview
| Uniprot ID | V9HWK1 |
|---|---|
| Protein Name | Triosephosphate isomerase |
| Gene Name | HEL-S-49 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 131 | VIACIGEKLDEREAG |
| 142 | REAGITEKVVFEQTK |
| 219 | SVTGATCKELASQPD |
| 33 | IGTLNAAKVPADTEV |
| 85 | EISPGMIKDCGATWV |
Function
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids
Protein Sequence
10
MAPSRKFFVG
20
GNWKMNGRKQ
30
SLGELIGTLN
40
AAKVPADTEV
50
VCAPPTAYID
60
FARQKLDPKI
70
AVAAQNCYKV
80
TNGAFTGEIS
90
PGMIKDCGAT
100
WVVLGHSERR
110
HVFGESDELI
120
GQKVAHALAE
130
GLGVIACIGE
140
KLDEREAGIT
150
EKVVFEQTKV
160
IADNVKDWSK
170
VVLAYEPVWA
180
IGTGKTATPQ
190
QAQEVHEKLR
200
GWLKSNVSDA
210
VAQSTRIIYG
220
GSVTGATCKE
230
LASQPDVDGF
240
LVGGASLKPE
FVDIINAKQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Molecular Function | GO:0008929 | methylglyoxal synthase activity |
| Molecular Function | GO:0004807 | triose-phosphate isomerase activity |
| Biological Process | GO:0061621 | canonical glycolysis |
| Biological Process | GO:0006094 | gluconeogenesis |
| Biological Process | GO:0019682 | glyceraldehyde-3-phosphate metabolic process |
Reference
PMID: N/A