Search Results
Overview
| Uniprot ID | W5HA06 |
|---|---|
| Protein Name | Histone H2B |
| Gene Name | LOC123161805 |
| Organism | Triticum aestivum |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 13 | EKKPVAEKAEKTTAA |
| 33 | EKRPPASKEGGEKKG |
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Protein Sequence
10
MAPKAEKKPV
20
AEKAEKTTAA
30
KKTKAEKRPP
40
ASKEGGEKKG
50
KKKSKKSVET
60
YKIYIFKVLK
70
QVHPDIGISS
80
KAMSIMNSFI
90
NDIFEKLAGE
100
SAKLARYNKK
110
PTITSREIQT
120
SVRLVLPGEL
130
AKHAVSEGTK
AVTKFTSS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000786 | nucleosome |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0030527 | structural constituent of chromatin |
| Biological Process | GO:0006325 | chromatin organization |
Reference
[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.