Search Results
Overview
| Uniprot ID | W5HZ15 |
|---|---|
| Protein Name | Histone H2B |
| Gene Name | LOC123165306 |
| Organism | Triticum aestivum |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 14 | KKPAAAEKTPAAEKT |
| 20 | EKTPAAEKTTAGKKP |
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling
Protein Sequence
10
MAPKAEKKPA
20
AAEKTPAAEK
30
TTAGKKPKAE
40
KRPPKSKEGG
50
ADKKKKKAKK
60
SVETYKIYIF
70
KVLKQVHPDI
80
GISSKAMSIM
90
NSFINDIFEK
100
LAGESAKLAR
110
YNKKPTITSR
120
EIQTSVRLVL
130
PGELAKHAVS
140
EGTKAVTKFT
SS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000786 | nucleosome |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0046982 | protein heterodimerization activity |
| Molecular Function | GO:0030527 | structural constituent of chromatin |
| Biological Process | GO:0006325 | chromatin organization |
Reference
[1] Zhu J, Guo W, Lan Y. Global Analysis of Lysine Lactylation of Germinated Seeds in Wheat.. Int J Mol Sci 24(22). 2023 Nov 11. PMID: 38003390.