Identification of lysine-lactylated substrates in gastric cancer cells
PMID: 35800753
DOI: 10.1016/j.isci.2022.104630
Authors: Yang D, Yin J, Shan L, Yi X, Zhang W et al
Journal: iScience (2022)
35800753_homo_sapiens — Homo sapiens
| Tissue or cell | AGS gastric cancer cells; gastric tumor and adjacent tissues for validation |
|---|---|
| Condition | Lactate/Kla profiling; tumor versus adjacent-tissue validation |
| Enrichment method | Anti-Kla antibody affinity enrichment |
| MS instrument | LC-MS/MS; instrument model Not reported |
| Search software | MaxQuant |
| Localization threshold | Localization probability >0.75 |
| FDR | Not reported |
| Source-reported sites / proteins | 2375 / 1014 |
| KlaDB-retained sites / proteins | 2365 / 1009 |
| Evidence source | 5 local files; primary article/source file: main.pdf |
| Curation notes | Counts are approximately consistent. Site-level provenance should still be represented through normalized Study and SiteEvidence records.; Repository/accession: PRJNA841340, PXD033991; Additional criterion: MaxQuant score ≥40 |