Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma

PMID: 36593272

DOI: 10.1038/s42255-022-00710-w

Authors: Yang Z, Yan C, Ma J, Peng P, Ren X et al

Journal: Nature metabolism (2023)

36593272_homo_sapiens — Homo sapiens

Tissue or cellHBV-related hepatocellular carcinoma and paired adjacent liver tissues
ConditionTumor versus paired adjacent liver; integrated lactylome and proteome analysis
Enrichment methodAnti-L-lactyllysine antibody (PTM-1401RM)
MS instrumentNot reported
Search softwareNot reported
Localization thresholdNot reported
FDRNot reported
Source-reported sites / proteins 9275 / Not reported
KlaDB-retained sites / proteins9211 / 2420
Evidence source22 local files; primary article/source file: 42255_2022_710_MOESM1_ESM.pdf
Curation notesThe local folder contains the reporting summary and supplementary files but not the main article PDF.; Repository/accession: OEP002852; Additional criterion: The local source folder lacks the main article PDF